XRCC3 antibody (C-Term)
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- Target See all XRCC3 Antibodies
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This XRCC3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Cross-Reactivity
- Human
- Characteristics
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Rabbit polyclonal antibody to XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3)
XRCC3 antibody [C1C3] - Purification
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the C-terminus region of human XRCC3. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product XRCC3 Primary Antibody
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- Application Notes
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Comment
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Positive Control: DDDDK-human XRCC3-transfected 293T cells
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
- Alternative Name
- X-ray repair cross complementing 3 (XRCC3 Products)
- Synonyms
- CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
- Background
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This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Cellular Localization: Nucleus - Molecular Weight
- 38 kDa
- Gene ID
- 7517
- UniProt
- O43542
- Pathways
- DNA Damage Repair
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