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XRCC3 antibody (C-Term)

XRCC3 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2857069
  • Target See all XRCC3 Antibodies
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    Binding Specificity
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 41
    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 6
    Rabbit
    Clonality
    • 38
    • 5
    Polyclonal
    Conjugate
    • 32
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This XRCC3 antibody is un-conjugated
    Application
    • 26
    • 15
    • 10
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human
    Characteristics
    Rabbit polyclonal antibody to XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3)
    XRCC3 antibody [C1C3]
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human XRCC3. The exact sequence is proprietary.
    Isotype
    IgG
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    Discover our top product XRCC3 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Comment

    Positive Control: DDDDK-human XRCC3-transfected 293T cells

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))
    Alternative Name
    X-ray repair cross complementing 3 (XRCC3 Products)
    Synonyms
    CMM6 antibody, 4432412E01Rik antibody, AI182522 antibody, AW537713 antibody, MGC69118 antibody, im:7142103 antibody, zgc:101608 antibody, si:dkey-11b8.1 antibody, xrcc3 antibody, XRCC3 antibody, X-ray repair cross complementing 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 antibody, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog antibody, XRCC3 antibody, Xrcc3 antibody, xrcc3.L antibody, xrcc3 antibody
    Background
    This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.

    Cellular Localization: Nucleus
    Molecular Weight
    38 kDa
    Gene ID
    7517
    UniProt
    O43542
    Pathways
    DNA Damage Repair
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