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ERCC8 antibody (Internal Region)

ERCC8 Reactivity: Human, Mouse WB, IF, ICC, Func Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2857082
  • Target See all ERCC8 Antibodies
    ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
    Binding Specificity
    • 15
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 46
    • 31
    • 22
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 40
    • 6
    Rabbit
    Clonality
    • 42
    • 4
    Polyclonal
    Conjugate
    • 27
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC8 antibody is un-conjugated
    Application
    • 46
    • 13
    • 13
    • 11
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Functional Studies (Func)
    Characteristics
    Rabbit Polyclonal antibody to ERCC8 (excision repair cross-complementing rodent repair deficiency, complementation group 8)
    ERCC8 antibody [N2C2], Internal
    Purification
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human ERCC8. The exact sequence is proprietary.
    Isotype
    IgG
    Top Product
    Discover our top product ERCC8 Primary Antibody
  • Application Notes
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Functional Assay Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000* Functional AssayAssay-dependent dilution
    Comment

    Positive Control: 293T , A431 , Neuro2A , GL261 , C8D30 , NIH-3T3, Raw264.7 , C2C12

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    1XPBS, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))
    Alternative Name
    ERCC8 (ERCC8 Products)
    Synonyms
    zgc:103550 antibody, CKN1 antibody, CSA antibody, UVSS2 antibody, Ckn1 antibody, 2410022P04Rik antibody, 2810431L23Rik antibody, 4631412O06Rik antibody, B130065P18Rik antibody, Csa antibody, excision repair cross-complementation group 8 antibody, ERCC excision repair 8, CSA ubiquitin ligase complex subunit antibody, excision repaiross-complementing rodent repair deficiency, complementation group 8 antibody, ercc8 antibody, ERCC8 antibody, Ercc8 antibody
    Background
    This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes.

    Cellular Localization: Nucleus
    Molecular Weight
    44 kDa
    Gene ID
    1161
    Pathways
    DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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