tau antibody

Catalog No. ABIN285974

Product Details anti-tau Antibody

Target: tau (tau Protein)

Reactivity: Mammalian

Host: Goat

Clonality: Polyclonal

Conjugate: This tau antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Tau antibody was raised in goat using a peptide, MAEPRQEFEVMEDHAG, as the immunogen.

Application Details

Application Notes: ELISA: >1:36,450, IHC-P: >1:200, WB: >1:4,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for tau

Target: tau (tau Protein)

Alternative Name: tau (tau Products)

Synonyms: DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody

Background: Tau is a heterogeneous group of proteins that range in molecular weight from 50-67 kDal. They are instrumental in the assembly of microtubules and have been associated with some disease states. In normal brain, tau is localized in the axons of the neurons, but in some neuropathological lesions, it accumulates with in the body of the neuron. Tau proteins are thought to be abnormally phosphorylated in certain disease states and are found associated with the deposits with the neuron. Tau has been immunohistochemically localized to neurofibrillary tangles of Alzheimer's disease (AD).