BNIP3 antibody (C-Term) (PE)
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- Target See all BNIP3 Antibodies
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BNIP3 antibody is conjugated to PE
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Predicted molecular weight at ~21.5 kDa. Observed bands at ~20-30 kDa and 50-60 kDa due to the homodimer complex of BNIP3.
- Cross-Reactivity
- Human, Mouse
- Purification
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the C-terminal of human BNIP3
- Top Product
- Discover our top product BNIP3 Primary Antibody
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN2869042 was sufficient for detection of BNIP3 on mouse kidney lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))
- Alternative Name
- BNIP3 (BNIP3 Products)
- Synonyms
- NIP3 antibody, Nip3 antibody, BCL2 interacting protein 3 antibody, BCL2/adenovirus E1B interacting protein 3 antibody, BNIP3 antibody, Bnip3 antibody
- Background
- BNIP3 is an apoptosis-inducing protein which can overcome BCL2 suppression. It may play a role in repartioning calcium between the two major intracellular calcium stores in association with BCL2. It has been shown to interact with CD47, BCL2-like, and BCL-2 (1-3).
- Gene ID
- 664
- NCBI Accession
- NP_004043
- UniProt
- Q12983
- Pathways
- Autophagy, Brown Fat Cell Differentiation
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