SLC2A2 antibody (C-Term) (FITC)
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- Target See all SLC2A2 Antibodies
- SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC2A2 antibody is conjugated to FITC
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Predicted molecular weight at ~57.5 kDa. Observed molecular weight at 60-70 kDa and 38-45 kDa.
- Cross-Reactivity
- Human, Rat
- Purification
- Peptide Affinity Purified
- Immunogen
- Synthetic peptide from the C-terminal of human GLUT2
- Top Product
- Discover our top product SLC2A2 Primary Antibody
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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A 1:1000 dilution of ABIN2869070 was sufficient for detection of GLUT2 on 293T Rapamycin-treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
- Alternative Name
- GLUT2 (SLC2A2 Products)
- Synonyms
- glut2 antibody, wu:fb62h10 antibody, slc2a2 antibody, MGC83262 antibody, SLC2A2 antibody, GLUT2 antibody, GTT2 antibody, Glut2 antibody, AI266973 antibody, Glut-2 antibody, solute carrier family 2 (facilitated glucose transporter), member 2 antibody, solute carrier family 2 member 2 L homeolog antibody, solute carrier family 2 member 2 antibody, solute carrier family 2, facilitated glucose transporter member 2 antibody, slc2a2 antibody, slc2a2.L antibody, SLC2A2 antibody, LOC100534484 antibody, Slc2a2 antibody
- Background
- Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and has a role in renal glucose reabsorption (1). Mutations in SLC2A2 lead to Fanconi-Bickel syndrome (FBS), which results in hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. Recent studies have shown that mutations in SLC2A2 can cause neonatal diabetes, and therefore may contribute to human insulin secretion (2). Novel SLC2A2 mutations have also been discovered and are being investigated to determine their roles in FBS as well (3).
- Gene ID
- 6514
- NCBI Accession
- NP_000331
- UniProt
- P11168
- Pathways
- Warburg Effect
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