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SLC2A2 antibody (C-Term) (FITC)

SLC2A2 Reactivity: Human WB, IF, ICC Host: Rabbit Polyclonal FITC
Catalog No. ABIN2869070
  • Target See all SLC2A2 Antibodies
    SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
    Binding Specificity
    • 17
    • 16
    • 15
    • 12
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 82
    • 41
    • 39
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 75
    • 6
    • 2
    • 2
    Rabbit
    Clonality
    • 76
    • 9
    Polyclonal
    Conjugate
    • 30
    • 6
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This SLC2A2 antibody is conjugated to FITC
    Application
    • 72
    • 49
    • 28
    • 26
    • 26
    • 16
    • 13
    • 11
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Predicted molecular weight at ~57.5 kDa. Observed molecular weight at 60-70 kDa and 38-45 kDa.
    Cross-Reactivity
    Human, Rat
    Purification
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the C-terminal of human GLUT2
    Top Product
    Discover our top product SLC2A2 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:1000 dilution of ABIN2869070 was sufficient for detection of GLUT2 on 293T Rapamycin-treated lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))
    Alternative Name
    GLUT2 (SLC2A2 Products)
    Synonyms
    glut2 antibody, wu:fb62h10 antibody, slc2a2 antibody, MGC83262 antibody, SLC2A2 antibody, GLUT2 antibody, GTT2 antibody, Glut2 antibody, AI266973 antibody, Glut-2 antibody, solute carrier family 2 (facilitated glucose transporter), member 2 antibody, solute carrier family 2 member 2 L homeolog antibody, solute carrier family 2 member 2 antibody, solute carrier family 2, facilitated glucose transporter member 2 antibody, slc2a2 antibody, slc2a2.L antibody, SLC2A2 antibody, LOC100534484 antibody, Slc2a2 antibody
    Background
    Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein facilitated glucose movement across cell membranes. It is the principal transporter for transfer of glucose between liver and blood, and has a role in renal glucose reabsorption (1). Mutations in SLC2A2 lead to Fanconi-Bickel syndrome (FBS), which results in hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. Recent studies have shown that mutations in SLC2A2 can cause neonatal diabetes, and therefore may contribute to human insulin secretion (2). Novel SLC2A2 mutations have also been discovered and are being investigated to determine their roles in FBS as well (3).
    Gene ID
    6514
    NCBI Accession
    NP_000331
    UniProt
    P11168
    Pathways
    Warburg Effect
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