DAT antibody, SLC6A3 antibody, Dat1 antibody, DAT1 antibody, PKDYS antibody, solute carrier family 6 member 3 antibody, solute carrier family 6 (neurotransmitter transporter), member 3 antibody, Sodium-dependent dopamine transporter antibody, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antibody, SLC6A3 antibody, slc6a3 antibody, dat-1 antibody, Slc6a3 antibody
Background
The dopamine transporter (also known as dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester DA and NE into vesicles for later storage and release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses except in the prefrontal cortex, where dopamine uptake via the norepinephrine transporter plays that role.