LTA antibody

Catalog No. ABIN289561

Product Details anti-LTA Antibody

Target: LTA (Lymphotoxin-alpha (LTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogen: TNF beta antibody was raised in rabbit using highly pure recombinant human TNF-beta as the immunogen.

Application Details

Application Notes: ELISA: 0.5-2 µg/mL, Inhibition:
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in sterile water to a concentration of > 0.2 mg/mL.

Concentration: Lot specific

Buffer: Lyophilized from 0.5 x PBS, pH 7.4.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for LTA

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: TNF beta (LTA Products)

Synonyms: LT antibody, TNFB antibody, TNFSF1 antibody, LT-[a] antibody, LT-alpha antibody, LT[a] antibody, LTalpha antibody, Ltx antibody, TNF-beta antibody, Tnfb antibody, Tnfsf1b antibody, hlb382 antibody, lymphotoxin alpha antibody, lymphotoxin A antibody, LTA antibody, Lta antibody

Target Type: Chemical

Background: TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha, TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta, which effectively anchors the TNF-beta to the cell surface.

Molecular Weight: 18.6 kDa (predicted detection band MW)

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process