Aurora A antibody

Catalog No. ABIN289985

Product Details anti-Aurora A Antibody

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: This antibody was purified from rabbit serum by affinity chromatography.

Immunogen: GST-Human Aurora-A fusion Protein

Application Details

Application Notes: Working dilution For western blotting , 0.5-2 ug/mlFor Immunohistochemistry , 1-2ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: Aurora-A (AURKA Products)

Synonyms: AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody

Background: Aurora-A (Aurora-A/STK-15/Aik) encoding a centrosome-associated kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. So that, Aurora-A is a potentialoncogene. Aurora family have been identified three types (Aurora-A, B, C) which has high homologydomain in C terminal region. Aurora family is indispensable kinase that regulate the structure and functionof centrosomes and spindle. Aurora-A could be one of targeting molecule of anti-cancer therapy.This antibody was established from the purified serum of the immunized rabbit with N terminal region ofAurora-A and did not show any cross- reactivity to Aurora-B and Aurora-C. This antibody is useful forwestern blotting and immunohistochemistry.

Pathways: Cell Division Cycle, Asymmetric Protein Localization