ADAMTS4 antibody (C-Term)

Catalog No. ABIN290073

Product Details anti-ADAMTS4 Antibody

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Binding Specificity: C-Term

Reactivity: Human, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human ADAMTS4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Predicted Reactivity: Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Dog, Horse (100%) Marmoset, Bat, Bovine, Elephant, Panda (94%) Monkey, Pig, Opossum (88%) Mouse, Rat, Hamster (82%).

Purification: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from C-terminus of human ADAMTS4. Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Dog, Horse (100%), Marmoset, Bat, Bovine, Elephant, Panda (94%), Monkey, Pig, Opossum (88%), Mouse, Rat, Hamster (82%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (20 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 20 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAMTS4

Target: ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))

Alternative Name: ADAMTS4 (ADAMTS4 Products)

Synonyms: 3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody

Background: Name/Gene ID: ADAMTS4
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAMTS4, ADAMTS-2, ADAMTS-4, ADAM-TS 4, ADAM-TS4, ADMP-1, Aggrecanase-1, KIAA0688

Gene ID: 9507