MAP3K7 antibody (AA 525-537)

Catalog No. ABIN291940

Product Details anti-MAP3K7 Antibody

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Binding Specificity: AA 525-537

Reactivity: Human, Mouse, Rat, Dog, Chicken, Xenopus laevis, Cow, Monkey, Pig, Bat, Hamster, Horse, Rabbit

Host: Goat

Clonality: Polyclonal

Conjugate: This MAP3K7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human MAP3K7 / TAK1. This antibody is expected to recognise isoform A (NP_003179.1) and isoform B (NP_663304.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Salmon, Stickleback, Pufferfish (100%) Zebrafish (92%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-AELDQDEKDQQNT from an internal region of human MAP3K7 / TAK1 (NP_003179.1, NP_663304.1). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Salmon, Stickleback, Pufferfish (100%), Zebrafish (92%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:1000), WB (1:1000, 1 - 3 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for MAP3K7

Target: MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

Alternative Name: MAP3K7 / TAK1 (MAP3K7 Products)

Synonyms: si:ch211-225h9.1 antibody, zgc:110612 antibody, Tak1 antibody, MEKK7 antibody, TAK1 antibody, TGF1a antibody, B430101B05 antibody, C87327 antibody, mitogen-activated protein kinase kinase kinase 7 antibody, mitogen activated protein kinase kinase kinase 7 antibody, map3k7 antibody, Map3k7 antibody, MAP3K7 antibody

Background: Name/Gene ID: MAP3K7
Subfamily: MLK(MAP3K)
Family: Protein Kinase

Synonyms: MAP3K7, MEKK7, TGF-beta activated kinase 1, TGF1a, TAK1, TGF-beta-activated kinase 1

Gene ID: 6885

NCBI Accession: NP_003179, NP_663304

UniProt: O43318

Pathways: NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway