Abeta 1-40 antibody

Catalog No. ABIN2961827

Product Details anti-Abeta 1-40 Antibody

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Abeta 1-40 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Specificity: Reacts with human and mouse Aβx-40

Purification: Purified

Immunogen: Synthetic peptide corresponding to Abeta35-40.

Clone: Ab40-1

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL for any application

Restrictions: For Research Use only

Handling

Buffer: PBS pH 7.4

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Stable for at least one year at -20°C

Expiry Date: 12 months

Target Details for Abeta 1-40

Target: Abeta 1-40 (Amyloid beta 1-40 (Abeta 1-40))

Alternative Name: Amyloid beta 1-40 (Abeta 1-40 Products)

Synonyms: AAA antibody, ABETA antibody, ABPP antibody, AD1 antibody, APPI antibody, CTFgamma antibody, CVAP antibody, PN-II antibody, PN2 antibody, amyloid beta precursor protein antibody, APP antibody

Background: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. There is a strong correlation between Aβ40 positivity and mature plaques. In the AD cortex, diffuse plaques, representing the earliest stage of Aβ deposition, are positive for Aβ42, but negative for Aβ40.

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 40 Beta-APP40 Gene name: APP, A4, AD1

Gene ID: 351

UniProt: P05067