Cytokeratin 7 antibody (AA 230-469)

Catalog No. ABIN3016271

Product Details anti-Cytokeratin 7 Antibody

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Binding Specificity: AA 230-469

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: ETELTELQSQ ISDTSVVLSM DNSRSLDLDG IIAEVKAQYE EMAKCSRAEA EAWYQTKFET LQAQAGKHGD DLRNTRNEIS EMNRAIQRLQ AEIDNIKNQR AKLEAAIAEA EERGELALKD ARAKQEELEA ALQRGKQDMA RQLREYQELM SVKLALDIEI ATYRKLLEGE ESRLAGDGVG AVNISVMNST GGSSSGGGIG LTLGGTMGSN ALSFSSSAGP GLLKAYSIRT ASASRRSARD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-469 of human Cytokeratin 7 (Cytokeratin 7 (KRT7)) (NP_005547.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-Cytokeratin 7 antibody (ABIN3016271)

Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin: "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 340-352, (2018) (PubMed).

Target Details for Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Alternative Name: KRT7 (KRT7 Products)

Synonyms: CK7 antibody, K2C7 antibody, K7 antibody, SCL antibody, D15Wsu77e antibody, Krt2-7 antibody, KRT7 antibody, keratin 7 antibody, KRT7 antibody, Krt7 antibody

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants, however, not all variants have been fully described.,KRT7,CK7,K2C7,K7,SCL,keratin 7,Keratin,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Extracellular Matrix,Cytokeratin,Keratin,KRT7

Molecular Weight: 51 kDa

Gene ID: 3855

UniProt: P08729