PARD6A antibody

Catalog No. ABIN3017296

Product Details anti-PARD6A Antibody

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARD6A antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide of human PARD6A

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PARD6A

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Alternative Name: PARD6A (PARD6A Products)

Synonyms: PARD6A antibody, 0710008C04Rik antibody, 2610010A15Rik antibody, PAR6alpha antibody, Par-6 antibody, Par6 antibody, Par6c antibody, TAX40 antibody, Tip-40 antibody, Par-6a antibody, Par6a antibody, PAR-6A antibody, PAR6 antibody, PAR6C antibody, TIP-40 antibody, par-6 partitioning defective 6 homolog alpha (C. elegans) antibody, par-6 family cell polarity regulator alpha antibody, Partitioning defective protein 6 antibody, PARD6A antibody, Pard6a antibody, par-6 antibody

Background: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,PARD6A,PAR-6A,PAR6,PAR6C,PAR6alpha,TAX40,TIP-40,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cell differentiation,Cell Adhesion,Tight Junctions,Cytoskeleton,TGF-b-Smad Signaling Pathway,Stem Cells,Cancer Stem Cells,PARD6A

Molecular Weight: 37 kDa

Gene ID: 50855

UniProt: Q9NPB6

Pathways: Cell-Cell Junction Organization