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DcR1 antibody

TNFRSF10C Reactivity: Human FACS Host: Mouse Monoclonal TRAIL-R3-02 unconjugated
Catalog No. ABIN301991
  • Target See all DcR1 (TNFRSF10C) Antibodies
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Reactivity
    • 59
    • 7
    • 7
    • 6
    Human
    Host
    • 41
    • 23
    • 1
    • 1
    Mouse
    Clonality
    • 43
    • 23
    Monoclonal
    Conjugate
    • 32
    • 8
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DcR1 antibody is un-conjugated
    Application
    • 40
    • 24
    • 23
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The antibody TRAIL-R3-02 reacts with TRAIL-R3, a 35 kDa GPI-anchored extracellular membrane protein expressed mainly on neutrophils.
    Cross-Reactivity (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Purity
    > 95 % (by SDS-PAGE)
    Immunogen
    TRAIL-R3-hIgGhc fusion protein
    Clone
    TRAIL-R3-02
    Isotype
    IgG1
    Top Product
    Discover our top product TNFRSF10C Primary Antibody
  • Application Notes
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Preservative
    Azide free
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 2-8°C. Do not freeze.
  • Target
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Alternative Name
    CD263 / TRAIL-R3 (TNFRSF10C Products)
    Synonyms
    CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
    Background
    TNF receptor superfamily member 10c,TRAIL-R3 (CD263, TR3, DcR1, LIT, TRID), expressed mainly on neutrophils, belongs to receptors of TRAIL, a TNF-like membrane cytotoxic protein that induces apoptosis in many tumour cells, but not in normal cells. TRAIL-R3, however, is a GPI-anchored protein that lacks cytoplasmic death domain, thus it is unable to induce apoptosis and serves as a negative regulator of apoptotic signaling by competing for binding of TRAIL with death receptor 5 (DR5).,TNFRSF10C, DcR1, TRAIL-R3, TRID, LIT
    Gene ID
    8794
    UniProt
    O14798
    Pathways
    Apoptosis
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