TUBA4A antibody (AA 1-180)

Catalog No. ABIN3020550

Product Details anti-TUBA4A Antibody

Target: TUBA4A (Tubulin, alpha 4a (TUBA4A))

Binding Specificity: AA 1-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBA4A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MRECISVHVG QAGVQMGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFT TFFCETGAGK HVPRAVFVDL EPTVIDEIRN GPYRQLFHPE QLITGKEDAA NNYARGHYTI GKEIIDPVLD RIRKLSDQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Loading control Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human alpha-Tubulin (NP_005991.1).

Isotype: IgG

Application Details

Application Notes: WB,1:2000 - 1:10000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-TUBA4A antibody (ABIN3020550)

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Zou, Wang, Hu, Zheng, Xu, Li: "Specific tumor-derived CCL2 mediated by pyruvate kinase M2 in colorectal cancer cells contributes to macrophage recruitment in tumor microenvironment." in: Tumour biology, Vol. 39, Issue 3, pp. 1010428317695962, (2017) (PubMed).

Jia, Kavungal, Jiang, Zhao, Sun, Wang, Song: "The characterization of hematopoietic tissue in adult Chinese mitten crab Eriocheir sinensis." in: Developmental and comparative immunology, Vol. 60, pp. 12-22, (2016) (PubMed).

Ye, Jiang, Cui, Zhu, Sun, Wang, Zohaib, Dong, Ruan, Song, He, Chen, Cao: "Etanercept reduces neuroinflammation and lethality in mouse model of Japanese encephalitis." in: The Journal of infectious diseases, Vol. 210, Issue 6, pp. 875-89, (2014) (PubMed).

Target Details for TUBA4A

Target: TUBA4A (Tubulin, alpha 4a (TUBA4A))

Alternative Name: TUBA4A (TUBA4A Products)

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulin. The genes encoding these microtubule constituents are part of the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes and they are highly conserved among and between species. This gene encodes an alpha tubulin that is a highly conserved homolog of a rat testis-specific alpha tubulin. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,TUBA4A,ALS22,H2-ALPHA,TUBA1,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Cytoskeleton,Microtubules,TUBA4A

Molecular Weight: 48 kDa/49 kDa

Gene ID: 7277

UniProt: P68366

Pathways: Microtubule Dynamics, M Phase