PSMD4/ASF antibody (AA 1-377)

Catalog No. ABIN3021330

Product Details anti-PSMD4/ASF Antibody

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Binding Specificity: AA 1-377

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD4/ASF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequence: MVLESTMVCV DNSEYMRNGD FLPTRLQAQQ DAVNIVCHSK TRSNPENNVG LITLANDCEV LTTLTPDTGR ILSKLHTVQP KGKITFCTGI RVAHLALKHR QGKNHKMRII AFVGSPVEDN EKDLVKLAKR LKKEKVNVDI INFGEEEVNT EKLTAFVNTL NGKDGTGSHL VTVPPGPSLA DALISSPILA GEGGAMLGLG ASDFEFGVDP SADPELALAL RVSMEEQRQR QEEEARRAAA ASAAEAGIAT TGTEDSDDAL LKMTISQQEF GRTGLPDLSS MTEEEQIAYA MQMSLQGAEF GQAESADIDA SSAMDTSEPA KEEDDYDVMQ DPEFLQSVLE NLPGVDPNNE AIRNAMGSLA SQATKDGKKD KKEEDKK

Cross-Reactivity: Human, Monkey, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human PSMD4 (NP_002801.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PSMD4/ASF

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Alternative Name: PSMD4 (Psmd4 Products)

Synonyms: af-1 antibody, mcb1 antibody, pub-r5 antibody, rpn10 antibody, PSMD4 antibody, DDBDRAFT_0202512 antibody, DDBDRAFT_0232981 antibody, DDB_0202512 antibody, DDB_0232981 antibody, AF antibody, AF-1 antibody, ASF antibody, MCB1 antibody, Rpn10 antibody, S5A antibody, pUB-R5 antibody, xrpn10c antibody, Af1 antibody, Mcb1 antibody, angiocidin antibody, im:6912672 antibody, psmd4 antibody, wu:fc68c04 antibody, zgc:110247 antibody, proteasome 26S subunit, non-ATPase 4 antibody, 26S proteasome non-ATPase regulatory subunit 4 antibody, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antibody, proteasome 26S subunit, non-ATPase 4 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antibody, proteasome 26S subunit, non-ATPase 4b antibody, psmd4 antibody, PSMD4 antibody, LOC100194679 antibody, psmD4 antibody, LOC100283637 antibody, Smp_000740.1 antibody, psmd4.L antibody, Psmd4 antibody, psmd4b antibody

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.,PSMD4,AF,AF-1,ASF,MCB1,Rpn10,S5A,pUB-R5,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,PSMD4

Molecular Weight: 28 kDa/40 kDa

Gene ID: 5710

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway