HNRNPA2B1 antibody (AA 1-180)

Catalog No. ABIN3021593

Product Details anti-HNRNPA2B1 Antibody

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Binding Specificity: AA 1-180

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MEREKEQFRK LFIGGLSFET TEESLRNYYE QWGKLTDCVV MRDPASKRSR GFGFVTFSSM AEVDAAMAAR PHSIDGRVVE PKRAVAREES GKPGAHVTVK KLFVGGIKED TEEHHLRDYF EEYGKIDTIE IITDRQSGKK RGFGFVTFDD HDPVDKIVLQ KYHTINGHNA EVRKALSRQE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human HNRNPA2B1 (NP_002128.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-HNRNPA2B1 antibody (ABIN3021593)

Wei, Dai, Zhou, He, Yao, Zhao, Guo, Yang: "Oroxylin A activates PKM1/HNF4 alpha to induce hepatoma differentiation and block cancer progression." in: Cell death & disease, Vol. 8, Issue 7, pp. e2944, (2018) (PubMed).

Target Details for HNRNPA2B1

Target: HNRNPA2B1 (Heterogeneous Nuclear Ribonucleoprotein A2/B1 (HNRNPA2B1))

Alternative Name: HNRNPA2B1 (HNRNPA2B1 Products)

Synonyms: HNRNPA2 antibody, HNRNPB1 antibody, HNRPA2 antibody, HNRPA2B1 antibody, HNRPB1 antibody, RNPA2 antibody, SNRPB1 antibody, hnrpa2b1 antibody, MGC53135 antibody, HNRNPA2B1 antibody, hnrnpa2 antibody, hnrnpb1 antibody, hnrpa2 antibody, hnrpb1 antibody, rnpa2 antibody, snrpb1 antibody, 9130414A06Rik antibody, Hnrpa2 antibody, Hnrpa2b1 antibody, hnrnp-A antibody, hnRNP antibody, heterogeneous nuclear ribonucleoprotein A2/B1 antibody, heterogeneous nuclear ribonucleoprotein A2/B1 S homeolog antibody, heterogeneous nuclear ribonucleoproteins A2/B1 antibody, HNRNPA2B1 antibody, hnrnpa2b1.S antibody, hnrnpa2b1 antibody, Hnrnpa2b1 antibody, LOC100353281 antibody

Background: This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms.,HNRNPA2,HNRNPB1,HNRPA2,HNRPA2B1,HNRPB1,IBMPFD2,RNPA2,SNRPB1,HNRNPA2B1,Epigenetics & Nuclear Signaling,RNA Binding,HNRNPA2B1

Molecular Weight: 36 kDa/37 kDa

Gene ID: 3181

UniProt: P22626