Ataxin 3 antibody (AA 1-364)

Catalog No. ABIN3021829

Product Details anti-Ataxin 3 Antibody

Target: Ataxin 3 (ATXN3)

Binding Specificity: AA 1-364

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ataxin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MESIFHEKQE GSLCAQHCLN NLLQGEYFSP VELSSIAHQL DEEERMRMAE GGVTSEDYRT FLQQPSGNMD DSGFFSIQVI SNALKVWGLE LILFNSPEYQ RLRIDPINER SFICNYKEHW FTVRKLGKQW FNLNSLLTGP ELISDTYLAL FLAQLQQEGY SIFVVKGDLP DCEADQLLQM IRVQQMHRPK LIGEELAQLK EQRVHKTDLE RVLEANDGSG MLDEDEEDLQ RALALSRQEI DMEDEEADLR RAIQLSMQGS SRNISQDMTQ TSGTNLTSEE LRKRREAYFE KQQQKQQQQQ QQQQQGDLSG QSSHPCERPA TSSGALGSDL GDAMSEEDML QAAVTMSLET VRNDLKTEGK K

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-364 of human Ataxin 3 (NP_004984.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Ataxin 3

Target: Ataxin 3 (ATXN3)

Alternative Name: ATXN3 (ATXN3 Products)

Synonyms: Mjd antibody, zgc:56323 antibody, ATXN3 antibody, at3 antibody, jos antibody, mjd antibody, atx3 antibody, mjd1 antibody, sca3 antibody, ataxin-3 antibody, MJD1 antibody, MGC83584 antibody, AT3 antibody, ATX3 antibody, JOS antibody, MJD antibody, SCA3 antibody, 2210008M02Rik antibody, AI463012 antibody, AI647473 antibody, Sca3 antibody, Rsca3 antibody, ataxin 3 antibody, ataxin 3 L homeolog antibody, ataxin-3 antibody, atxn3 antibody, ATXN3 antibody, atxn3.L antibody, MICPUN_104046 antibody, MICPUCDRAFT_46658 antibody, Atxn3 antibody

Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,ATXN3,AT3,ATX3,JOS,MJD,MJD1,SCA3,ataxin-3,Ataxin 3,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Neurodegenerative Diseases,ATXN3

Molecular Weight: 20 kDa/35 kDa/39 kDa/41 kDa

Gene ID: 4287

UniProt: P54252