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NOD1 antibody (AA 1-270)

NOD1 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3021837
  • Target See all NOD1 Antibodies
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Binding Specificity
    • 12
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270
    Reactivity
    • 43
    • 21
    • 14
    Human
    Host
    • 46
    • 3
    • 1
    Rabbit
    Clonality
    • 49
    • 1
    Polyclonal
    Conjugate
    • 28
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOD1 antibody is un-conjugated
    Application
    • 41
    • 23
    • 9
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    MEEQGHSEME IIPSESHPHI QLLKSNRELL VTHIRNTQCL VDNLLKNDYF SAEDAEIVCA CPTQPDKVRK ILDLVQSKGE EVSEFFLYLL QQLADAYVDL RPWLLEIGFS PSLLTQSKVV VNTDPVSRYT QQLRHHLGRD SKFVLCYAQK EELLLEEIYM DTIMELVGFS NESLGSLNSL ACLLDHTTGI LNEQGETIFI LGDAGVGKSM LLQRLQSLWA TGRLDAGVKF FFHFRCRMFS CFKESDRLCL QDLLFKHYCY PERDPEEVFA
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human NOD1 (NP_006083.1).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IHC,1:50 - 1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
    Alternative Name
    NOD1 (NOD1 Products)
    Synonyms
    CARD4 antibody, CLR7.1 antibody, NLRC1 antibody, C230079P11 antibody, Card4 antibody, F830007N14Rik antibody, Nlrc1 antibody, RGD1562269 antibody, nucleotide binding oligomerization domain containing 1 antibody, nucleotide-binding oligomerization domain containing 1 antibody, NOD1 antibody, Nod1 antibody
    Background
    This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.,NOD1,CARD4,CLR7.1,NLRC1,Cell Biology & Developmental Biology,Apoptosis,Caspases,NOD1
    Molecular Weight
    27 kDa/107 kDa
    Gene ID
    10392
    UniProt
    Q9Y239
    Pathways
    Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
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