Tryptophan Hydroxylase 1 antibody (AA 345-444)

Catalog No. ABIN3022155

Product Details anti-Tryptophan Hydroxylase 1 Antibody

Target: Tryptophan Hydroxylase 1 (TPH1)

Binding Specificity: AA 345-444

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Tryptophan Hydroxylase 1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSGHAKVKPF DPKITCKQEC LITTFQDVYF VSESFEDAKE KMREFTKTIK RPFGVKYNPY TRSIQILKDT KSITSAMNEL QHDLDVVSDA LAKVSRKPSI

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 345-444 of human TPH1 (NP_004170.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Tryptophan Hydroxylase 1

Target: Tryptophan Hydroxylase 1 (TPH1)

Alternative Name: TPH1 (TPH1 Products)

Synonyms: TPRH antibody, TRPH antibody, tph antibody, tph1 antibody, tphD1 antibody, tph2 antibody, tph1l antibody, tphD2 antibody, Tph antibody, TPH antibody, SERGEF antibody, LOC100229598 antibody, tryptophan hydroxylase 1 antibody, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a antibody, TryPtophan Hydroxylase antibody, tryptophan hydroxylase 1b antibody, tryptophan hydroxylase 1 L homeolog antibody, tryptophan 5-hydroxylase 1 antibody, TPH1 antibody, tph1a antibody, tph-1 antibody, tph1b antibody, Tph1 antibody, tph1.L antibody, LOAG_02149 antibody, Tsp_05203 antibody

Background: This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.,TPH1,TPRH,TRPH,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Neuroscience,TPH1

Molecular Weight: 50 kDa/53 kDa

Gene ID: 7166

UniProt: P17752

Pathways: Feeding Behaviour