Paired Box 3 antibody (AA 1-206)

Catalog No. ABIN3022376

Product Details anti-Paired Box 3 Antibody

Target: Paired Box 3 (PAX3)

Binding Specificity: AA 1-206

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Paired Box 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MTTLAGAVPR MMRPGPGQNY PRSGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPKQVT TPDVEKKIEE YKRENPGMFS WEIRDKLLKD AVCDRNTVPS VSSISRILRS KFGKGEEEEA DLERKEAEES EKKAKHSIDG ILSERGKALV SGVSSH

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-206 of human PAX3 (NP_039230.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Paired Box 3

Target: Paired Box 3 (PAX3)

Alternative Name: PAX3 (PAX3 Products)

Synonyms: PAX3 antibody, cdhs antibody, hup2 antibody, pax-3 antibody, ws1 antibody, xpax3 antibody, Pax3 antibody, pax3 antibody, pax3b antibody, xPax3-B antibody, CDHS antibody, HUP2 antibody, WS1 antibody, WS3 antibody, Pax-3 antibody, Sp antibody, splotch antibody, zgc:92547 antibody, paired box 3 antibody, paired box 3 L homeolog antibody, paired box 3a antibody, PAX3 antibody, pax3 antibody, pax3.L antibody, Pax3 antibody, pax3a antibody

Background: This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.,PAX3,CDHS,HUP2,WS1,WS3,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Stem Cells,Mesenchymal Stem Cells,Neural Stem Cells,PAX3

Molecular Weight: 22 kDa/24 kDa/44 kDa/45 kDa/52 kDa/53 kDa/55 kDa

Gene ID: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation