ERCC3 antibody (AA 513-782)

Catalog No. ABIN3022427

Product Details anti-ERCC3 Antibody

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Binding Specificity: AA 513-782

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PMSPEFYREY VAIKTKKRIL LYTMNPNKFR ACQFLIKFHE RRNDKIIVFA DNVFALKEYA IRLNKPYIYG PTSQGERMQI LQNFKHNPKI NTIFISKVGD TSFDLPEANV LIQISSHGGS RRQEAQRLGR VLRAKKGMVA EEYNAFFYSL VSQDTQEMAY STKRQRFLVD QGYSFKVITK LAGMEEEDLA FSTKEEQQQL LQKVLAATDL DAEEEVVAGE FGSRSSQASR RFGTMSSMSG ADDTVYMEYH SSRSKAPSKH VHPLFKRFRK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 513-782 of human ERCC3 (NP_000113.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERCC3

Target: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Alternative Name: ERCC3 (ERCC3 Products)

Synonyms: BTF2 antibody, GTF2H antibody, RAD25 antibody, TFIIH antibody, XPB antibody, BTF2 p89 antibody, Ercc-3 antibody, wu:fc25f08 antibody, ERCC excision repair 3, TFIIH core complex helicase subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 3 antibody, excision repair cross-complementation group 3 antibody, ERCC3 antibody, Ercc3 antibody, ercc3 antibody

Background: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.,ERCC3,BTF2,GTF2H,RAD25,TFIIH,TTD2,XPB,Epigenetics & Nuclear Signaling,Transcription Factors,DNA Damage & Repair,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Nucleotide metabolism,Purine and pyrimidine synthesis,ERCC3

Molecular Weight: 89 kDa

Gene ID: 2071

UniProt: P19447

Pathways: DNA Damage Repair