Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Phospholipase C gamma 2 antibody (AA 1-300)

PLCG2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023145
  • Target See all Phospholipase C gamma 2 (PLCG2) Antibodies
    Phospholipase C gamma 2 (PLCG2)
    Binding Specificity
    • 31
    • 22
    • 16
    • 16
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-300
    Reactivity
    • 130
    • 67
    • 53
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Human
    Host
    • 124
    • 6
    Rabbit
    Clonality
    • 120
    • 10
    Polyclonal
    Conjugate
    • 59
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    This Phospholipase C gamma 2 antibody is un-conjugated
    Application
    • 95
    • 40
    • 40
    • 36
    • 35
    • 23
    • 19
    • 17
    • 11
    • 7
    • 5
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    MSTTVNVDSL AEYEKSQIKR ALELGTVMTV FSFRKSTPER RTVQVIMETR QVAWSKTADK IEGFLDIMEI KEIRPGKNSK DFERAKAVRQ KEDCCFTILY GTQFVLSTLS LAADSKEDAV NWLSGLKILH QEAMNASTPT IIESWLRKQI YSVDQTRRNS ISLRELKTIL PLINFKVSSA KFLKDKFVEI GAHKDELSFE QFHLFYKKLM FEQQKSILDE FKKDSSVFIL GNTDRPDASA VYLHDFQRFL IHEQQEHWAQ DLNKVRERMT KFIDDTMRET AEPFLFVDEF LTYLFSRENS
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PLC gamma 2 (PLC gamma 2 (PLCG2)) (NP_002652.2).
    Isotype
    IgG
  • Application Notes
    WB,1:500 - 1:2000,IF,1:20 - 1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Phospholipase C gamma 2 (PLCG2)
    Alternative Name
    PLCG2 (PLCG2 Products)
    Synonyms
    PLCgamma2 antibody, Plcg-2 antibody, APLAID antibody, FCAS3 antibody, phospholipase C, gamma 2 antibody, phospholipase C gamma 2 antibody, phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody, Plcg2 antibody, PLCG2 antibody
    Background
    The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.,PLCG2,APLAID,FCAS3,PLC-IV,PLC-gamma-2,Cancer,Signal Transduction,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Lipid Metabolism,Hydrolysis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Cardiovascular,Angiogenesis,Lipids,PLCG2
    Molecular Weight
    147 kDa
    Gene ID
    5336
    UniProt
    P16885
    Pathways
    RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Toll-Like Receptors Cascades, VEGF Signaling, BCR Signaling
You are here:
Support