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RAPGEF3 antibody (AA 1-200)

RAPGEF3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023196
  • Target See all RAPGEF3 Antibodies
    RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
    Binding Specificity
    • 15
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200
    Reactivity
    • 55
    • 39
    • 32
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 53
    • 2
    Rabbit
    Clonality
    • 43
    • 12
    Polyclonal
    Conjugate
    • 25
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAPGEF3 antibody is un-conjugated
    Application
    • 27
    • 17
    • 13
    • 13
    • 12
    • 11
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    MVLRRMHRPR SCSYQLLLEH QRPSCIQGLR WTPLTNSEES LDFSESLEQA STERVLRAGR QLHRHLLATC PNLIRDRKYH LRLYRQCCSG RELVDGILAL GLGVHSRSQV VGICQVLLDE GALCHVKHDW AFQDRDAQFY RFPGPEPEPV GTHEMEEELA EAVALLSQRG PDALLTVALR KPPGQRTDEE LDLIFEELLH
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Epac1/Epac1/RAPGEF3 (NP_001092002.1).
    Isotype
    IgG
    Top Product
    Discover our top product RAPGEF3 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RAPGEF3 (Rap Guanine Nucleotide Exchange Factor (GEF) 3 (RAPGEF3))
    Alternative Name
    RAPGEF3 (RAPGEF3 Products)
    Synonyms
    RAPGEF3 antibody, epac antibody, si:dkey-27m20.2 antibody, CAMP-GEFI antibody, EPAC antibody, EPAC1 antibody, HSU79275 antibody, bcm910 antibody, 2310016P22Rik antibody, 9330170P05Rik antibody, Epac antibody, Epac1 antibody, Rap guanine nucleotide exchange factor 3 antibody, Rap guanine nucleotide exchange factor 3 S homeolog antibody, Rap guanine nucleotide exchange factor (GEF) 3 antibody, RAPGEF3 antibody, rapgef3.S antibody, rapgef3 antibody, Rapgef3 antibody
    Background
    Guanine nucleotide exchange factor (GEF for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin.,RAPGEF3,CAMP-GEFI,EPAC,EPAC1,HSU79275,bcm910,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,MAPK-Erk Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,RAPGEF3
    Molecular Weight
    66 kDa/99 kDa/103 kDa
    Gene ID
    10411
    UniProt
    O95398
    Pathways
    cAMP Metabolic Process
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