MAPK14 antibody (Mitogen-Activated Protein Kinase 14)

Details for Product anti-MAPK14 Antibody No. ABIN3023295, Supplier: Log in to see
Antigen
  • CSBP
  • CSBP1
  • CSBP2
  • CSPB1
  • EXIP
  • Mxi2
  • PRKM14
  • PRKM15
  • RK
  • SAPK2A
  • p38
  • p38ALPHA
  • CRK1
  • Csbp1
  • Csbp2
  • Exip
  • Hog
  • Prkm14
  • Prkm15
  • Sapk2A
  • p38Hog
  • p38alpha
  • p38b
  • zp38b
  • MAPK14
  • 186F5S
  • BG:DS00797.3
  • CG7393
  • D-p38
  • D-p38 MAPK
  • D-p38b
  • Dm p38b
  • Dmel\\CG7393
  • Dmp38b
  • Dp38
  • Dp38b
  • ESTS:186F5S
  • Mpk34C
  • anon-sts23
  • dp38b
  • p38 MAPK
  • p38 beta
  • p38B
  • p38Kb
  • p38beta
  • Crk1
  • p38-alpha
  • p38MAPK
  • p38a
  • csbp
  • mapk14a
  • mxi2
  • sapk2
  • sapk2a
  • AP22.98
  • AP22_98
  • ATMPK14
  • mitogen-activated protein kinase 14
  • SAPK2a
  • MAP kinase 14A
  • MAP kinase p38a
  • MAPK 14A
  • fk28c03
  • hm:zeh1243
  • wu:fk28c03
  • zp38a
  • mitogen-activated protein kinase 14
  • mitogen activated protein kinase 14
  • mitogen-activated protein kinase 14b
  • p38b MAP kinase
  • mitogen-activated protein kinase 14 S homeolog
  • mitogen-activated protein kinase 14a
  • MAPK14
  • Mapk14
  • mapk14b
  • p38b
  • mapk14.S
  • MPK14
  • mapk14a
Alternatives
anti-Dog (Canine) MAPK14 antibody for Western Blotting
Reactivity
Mouse (Murine), Rat (Rattus), Human
320
139
135
23
17
17
14
11
11
10
7
7
5
5
3
3
2
1
1
1
Host
Rabbit
264
61
2
2
Clonality
Polyclonal
Conjugate
This MAPK14 antibody is un-conjugated
13
11
8
8
8
8
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
305
140
108
61
35
34
17
16
9
6
3
3
2
1
1
Options
Supplier
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Supplier Product No.
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Immunogen A synthetic peptide of human MAPK14
Isotype IgG
Purification Affinity purification
Plasmids, Primers & others Plasmids, Primers & others MAPK14 products on genomics-online (e.g. as negative or positive controls)
Antigen Mitogen-Activated Protein Kinase 14 (MAPK14)
Alternative Name MAPK14 (MAPK14 Antibody Abstract)
Background P38 MAP kinase (MAPK), also called RK or CSBP , is the mammalian orthologue of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress. Four isoforms of p38 MAPK, p38alpha, beta, gamma (also known as Erk6 or SAPK3), and delta (also known as SAPK4) have been identified. Similar to the SAPK/JNK pathway, p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharide (LPS), UV light, and growth factors. MKK3, MKK6, and SEK activate p38 MAPK by phosphorylation at Thr180 and Tyr182. Activated p38 MAPK has been shown to phosphorylate and activate MAPKAP kinase 2 and to phosphorylate the transcription factors ATF-2 , Max , and MEF2.SB203580 (4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-imidazole) is a selective inhibitor of p38 MAPK. This compound inhibits the activation of MAPKAPK-2 by p38 MAPK and subsequent phosphorylation of HSP27. SB203580 inhibits p38 MAPK catalytic activity by binding to the ATP-binding pocket, but does not inhibit phosphorylation of p38 MAPK by upstream kinases.
Synonyms: MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, EXIP, Mxi2, PRKM14, PRKM15, RK, p38, p38ALPHA
Gene ID 1432
UniProt Q16539
Pathways MAPK Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling
Application Notes Recommended dilutions: WB: 1:500-1:2000, ICC: 1:50-1:100, IP: 1:10-1:100, FC: 1:50-1:200
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze / thaw cycles
Storage -20 °C/-80 °C
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody (ABIN3023295) Western blot analysis of extracts of various cell lines, using MAPK14 antibody.
Immunohistochemistry (IHC) image for anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody (ABIN3023295) anti-Mitogen-Activated Protein Kinase 14 (MAPK14) antibody (Image 2)
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