Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

ADAMTS4 antibody (AA 52-315)

ADAMTS4 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023337
  • Target See all ADAMTS4 Antibodies
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Binding Specificity
    • 15
    • 12
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-315
    Reactivity
    • 80
    • 48
    • 20
    • 10
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 72
    • 10
    • 4
    Rabbit
    Clonality
    • 77
    • 9
    Polyclonal
    Conjugate
    • 40
    • 10
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAMTS4 antibody is un-conjugated
    Application
    • 63
    • 29
    • 15
    • 13
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    ASPLPREEEI VFPEKLNGSV LPGSGAPARL LCRLQAFGET LLLELEQDSG VQVEGLTVQY LGQAPELLGG AEPGTYLTGT INGDPESVAS LHWDGGALLG VLQYRGAELH LQPLEGGTPN SAGGPGAHIL RRKSPASGQG PMCNVKAPLG SPSPRPRRAK RFASLSRFVE TLVVADDKMA AFHGAGLKRY LLTVMAAAAK AFKHPSIRNP VSLVVTRLVI LGSGEEGPQV GPSAAQTLRS FCAWQRGLNT PEDSDPDHFD TAIL
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 52-315 of human ADAMTS4 (NP_005090.3).
    Isotype
    IgG
    Top Product
    Discover our top product ADAMTS4 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    ADAMTS4 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4))
    Alternative Name
    ADAMTS4 (ADAMTS4 Products)
    Synonyms
    3830423K05 antibody, ADAM-TS4 antibody, ADAMTS-2 antibody, ADMP-1 antibody, mKIAA0688 antibody, ADAMTS-4 antibody, ADAMTS4 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 4 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 4 antibody, Adamts4 antibody, ADAMTS4 antibody
    Background
    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradation of aggrecan. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,ADAMTS4,ADAMTS-2,ADAMTS-4,ADMP-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,ADAM Protein Family,MMPs,Ubiquitin,ADAMTS4
    Molecular Weight
    90 kDa
    Gene ID
    9507
    UniProt
    O75173
You are here:
Support