GNA11 antibody

Catalog No. ABIN3023415

Product Details anti-GNA11 Antibody

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNA11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human GNA11

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GNA11

Target: GNA11 (Guanine Nucleotide Binding Protein (G Protein), alpha 11 (Gq Class) (GNA11))

Alternative Name: GNA11 (GNA11 Products)

Synonyms: Dsk7 antibody, E430025L19 antibody, GNA-11 antibody, HHC2 antibody, HYPOC2 antibody, G-alpha-11 antibody, gna11 antibody, si:dkey-42p8.2 antibody, wu:fb12d06 antibody, zgc:101761 antibody, guanine nucleotide binding protein, alpha 11 antibody, G protein subunit alpha 11 antibody, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) antibody, guanine nucleotide regulatory protein G11 alpha subunit antibody, guanine nucleotide binding protein (G protein), alpha 11a (Gq class) antibody, guanine nucleotide binding protein (G protein), alpha 11 (Gq class) S homeolog antibody, guanine nucleotide binding protein (G protein), alpha 11b (Gq class) antibody, Gna11 antibody, GNA11 antibody, gna11 antibody, gna11a antibody, gna11.S antibody, gna11b antibody

Background: The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations.,GNA11,FBH,FBH2,FHH2,GNA-11,HHC2,HYPOC2,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,mTOR Signaling Pathway,GNA11

Molecular Weight: 42 kDa

Gene ID: 2767

UniProt: P29992

Pathways: G-protein mediated Events