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UACA antibody

UACA Reactivity: Human, Mouse WB, IF, FACS Host: Mouse Monoclonal UACA-1222 unconjugated
Catalog No. ABIN3024024
  • Target See all UACA Antibodies
    UACA
    Reactivity
    • 42
    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 28
    • 14
    Mouse
    Clonality
    • 30
    • 12
    Monoclonal
    Conjugate
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UACA antibody is un-conjugated
    Application
    • 36
    • 14
    • 13
    • 13
    • 11
    • 8
    • 7
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    Protein G affinity chromatography
    Immunogen
    Recombinant human protein was used as the immunogen for the UACA antibody.
    Clone
    UACA-1222
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product UACA Primary Antibody
  • Application Notes
    Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    UACA
    Alternative Name
    UACA (UACA Products)
    Synonyms
    NUCLING antibody, 2700059D02Rik antibody, nucling antibody, RGD1560011 antibody, uveal autoantigen with coiled-coil domains and ankyrin repeats antibody, UACA antibody, Uaca antibody
    Background
    UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
    Pathways
    Positive Regulation of Endopeptidase Activity
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