Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN3024030

Product Details anti-Uroplakin 3A Antibody

Target: Uroplakin 3A (UPK3A)

Binding Specificity: AA 260-279

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Protein A affinity chromatography

Immunogen: A synthetic peptide, aa 260-279 (GASESSYTSVNRGPPLDRAE) of human Uroplakin 3A was used as the immunogen for this antibody.

Isotype: IgG

Application Details

Application Notes: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,WB: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Uroplakin 3A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: Uroplakin 3A (UPK3A Products)

Synonyms: UP3A antibody, UPIII antibody, UPIIIA antibody, UPK3 antibody, upk3 antibody, upiii antibody, MGC75921 antibody, 1110017C07Rik antibody, UP3a antibody, Upk3 antibody, up3a antibody, upiiia antibody, upk3a antibody, xUPIII antibody, uroplakin 3A antibody, uroplakin 3 antibody, uroplakin 3A L homeolog antibody, UPK3A antibody, upk3a antibody, Upk3a antibody, LOC100008738 antibody, upk3a.L antibody

Background: Uroplakin 3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. Uroplakin 3A may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. Uroplakin 3A has been shown as a helpful marker for the detection of bladder cancer.

Gene ID: 7380