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MYH11 antibody

MYH11 Reactivity: Human, Rat IF, FACS, IHC (p) Host: Mouse Monoclonal MYH11-923 unconjugated
Catalog No. ABIN3026132
  • Target See all MYH11 Antibodies
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Reactivity
    • 41
    • 20
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    Human, Rat
    Host
    • 36
    • 8
    Mouse
    Clonality
    • 23
    • 21
    Monoclonal
    Conjugate
    • 27
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This MYH11 antibody is un-conjugated
    Application
    • 15
    • 13
    • 12
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Protein G affinity chromatography
    Immunogen
    Recombinant human protein was used as the immunogen for the SMMHC antibody.
    Clone
    MYH11-923
    Isotype
    IgG1
    Top Product
    Discover our top product MYH11 Primary Antibody
  • Application Notes
    Optimal dilution of the SMMHC antibody should be determined by the researcher.

    1. Staining of formalin/paraffin tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
    2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format: incubate for 30 min at RT (2)

    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    1 mg/mL in 1X PBS, BSA free, sodium azide free
    Preservative
    Azide free
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the SMMHC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    MYH11 (Myosin Heavy Chain 11, Smooth Muscle (MYH11))
    Alternative Name
    SMMHC (MYH11 Products)
    Synonyms
    AV071570 antibody, SM1 antibody, SM2 antibody, smMHC antibody, AAT4 antibody, FAA4 antibody, SMHC antibody, SMMHC antibody, myosin antibody, myh11 antibody, myosin, heavy polypeptide 11, smooth muscle antibody, myosin heavy chain 11 antibody, myosin, heavy chain 11, smooth muscle antibody, myosin, heavy chain 11a, smooth muscle antibody, Myh11 antibody, MYH11 antibody, myh11a antibody
    Background
    Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
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