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GAB1 antibody (GRB2-Associated Binding Protein 1) (pTyr659) Primary Antibody

GAB1 Reactivity: Human DB, ELISA Host: Rabbit Polyclonal
Catalog No. ABIN3028686
$452.38
Plus shipping costs $45.00
0.4 mL ABIN3028686
0.4 mL ABIN3028686
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  • Target
    Binding Specificity
    pTyr659
    Reactivity
    Human
    Host
    Rabbit
    Clonality
    Polyclonal
    Application
    Dot Blot (DB), ELISA
    Cross-Reactivity (Details)
    Expected species reactivity: Mouse, Bovine
    Purification
    Antigen affinity purified
    Immunogen
    This phospho-Gab1 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY659 of human Gab1.
    Isotype
    Ig Fraction
  • Target
    Alternative Name
    GAB1 (GAB1 Antibody Abstract)
    Background
    Gab1 is a member of the IRS1-like multisubstrate docking protein family. This protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis.
    UniProt
    Q13480
    Pathways
    RTK Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
  • Application Notes
    Titration of the phospho-Gab1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the phospho-Gab1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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