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C5 antibody (AA 1-77)

C5 Reactivity: Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029691
  • Target See all C5 Antibodies
    C5 (Complement Component 5 (C5))
    Binding Specificity
    • 23
    • 15
    • 15
    • 15
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-77
    Reactivity
    • 124
    • 32
    • 19
    • 16
    • 2
    • 2
    • 2
    Rat
    Host
    • 113
    • 15
    • 6
    • 4
    Rabbit
    Clonality
    • 123
    • 14
    Polyclonal
    Conjugate
    • 49
    • 13
    • 12
    • 9
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    This C5 antibody is un-conjugated
    Application
    • 69
    • 50
    • 42
    • 39
    • 26
    • 20
    • 12
    • 9
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    Rat partial recombinant protein (AA 1-77, alpha subunit) was used as the immunogen for this C5 antibody.
    Isotype
    IgG
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  • Application Notes
    Titration of the C5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    The C5 antibody can be stored at 4°C to -20°C. After reconsititution, aliquot and store at -20°C. Avoid repeated freeze/thaws.
  • Target
    C5 (Complement Component 5 (C5))
    Alternative Name
    C5 (C5 Products)
    Synonyms
    C5 antibody, LOC565774 antibody, C5a antibody, C5b antibody, CPAMD4 antibody, Hc antibody, RGD1561905 antibody, He antibody, complement C5 antibody, complement component 5 antibody, hemolytic complement antibody, C5 antibody, c5 antibody, Hc antibody
    Background
    C5a is a protein fragment released from complement component C5. The protein plays an important role in inflammatory and cell killing processes. C5 is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.
    Gene ID
    362119
    Pathways
    Complement System, Carbohydrate Homeostasis
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