ADAMTS1 antibody (AA 956-968)

Catalog No. ABIN3029863

Product Details anti-ADAMTS1 Antibody

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Binding Specificity: AA 956-968

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Amino acids 956-968 (KHYIDFCTLTQCS-mouse) were used as the immunogen for this ADAMTS1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ADAMTS1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ADAMTS1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ADAMTS1

Target: ADAMTS1 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 1 (ADAMTS1))

Alternative Name: ADAMTS1 (ADAMTS1 Products)

Synonyms: c3-c5 antibody, meth1 antibody, xadamts1 antibody, C3-C5 antibody, METH1 antibody, ADAM-TS1 antibody, ADAMTS antibody, ADAMTS-1 antibody, METH-1 antibody, adamts1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 1 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 1 L homeolog antibody, ADAMTS1 antibody, adamts1 antibody, Adamts1 antibody, adamts1.L antibody

Background: A Disintegrin-Like and Metalloproteinase with Thrombospondin Type 1 Motif, 1, also known as METH1, is an enzyme that in humans is encoded by the ADAMTS1 gene. ADAMTS is a family of proteins believed to be anchored to the extracellular matrix(ECM) through interactions with aggregan or other matrix components by one or more thrombospondin type 1 motifs. Scott(2000) mapped the gene to 21q21.2 based on sequence similarity between the ADAMTS1 sequence and a chromosome 21q21.2 clone. Kuno et al.(1997) found that mouse Adamts1 expression could be induced in vitro in colon adenocarcinoma cells by stimulation with the inflammatory cytokine interleukin 1-alpha, or in vivo in kidney and heart by intravenous administration of lipopolysaccharide. Vazquez et al.(1999) determined that ADAMTS1 disrupts angiogenesis in vivo and in vitro more efficiently than ADAMTS8, THBS1, or endostatin.

UniProt: P97857

Pathways: SARS-CoV-2 Protein Interactome