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FE65 antibody (AA 295-613)

APBB1 Reactivity: Mouse, Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3029930
  • Target See all FE65 (APBB1) Antibodies
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    Binding Specificity
    • 15
    • 15
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 295-613
    Reactivity
    • 55
    • 38
    • 27
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Mouse, Human
    Host
    • 58
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    This FE65 antibody is un-conjugated
    Application
    • 59
    • 39
    • 39
    • 14
    • 10
    • 9
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Purification
    Antigen affinity
    Immunogen
    Human partial recombinant protein (AA 295-613) was used as the immunogen for this FE65 antibody.
    Isotype
    IgG
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  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the FE65 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the FE65 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    FE65 (APBB1) (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65) (APBB1))
    Alternative Name
    FE65 (APBB1 Products)
    Synonyms
    FE65 antibody, MGC:9072 antibody, RIR antibody, apbb1 antibody, MGC80654 antibody, Fe65 antibody, Rir antibody, amyloid beta precursor protein binding family B member 1 antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) L homeolog antibody, amyloid beta (A4) precursor protein-binding, family B, member 1 antibody, APBB1 antibody, apbb1.L antibody, Apbb1 antibody
    Background
    APBB1 is also known as RIR or FE65. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimers disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimers disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Gene ID
    322
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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