ABCB6 antibody (C-Term)

Catalog No. ABIN3030052

Product Details anti-ABCB6 Antibody

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human ABCB6 (YADMWQLQQGQEETSEDTKPQTMER) was used as the immunogen for this ABCB6 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ABCB6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ABCB6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ABCB6

Target: ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))

Alternative Name: ABCB6 (ABCB6 Products)

Synonyms: ABCB6 antibody, abcb6 antibody, ABC antibody, ABC14 antibody, LAN antibody, MCOPCB7 antibody, MTABC3 antibody, PRP antibody, umat antibody, 1200005B17Rik antibody, ATP binding cassette subfamily B member 6 (Langereis blood group) antibody, ATP binding cassette subfamily B member 6 antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6a antibody, ATP-binding cassette, sub-family B (MDR/TAP), member 6 antibody, ABCB6 antibody, abcb6a antibody, abcb6 antibody, Abcb6 antibody

Background: ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.

UniProt: Q9NP58

Pathways: Transition Metal Ion Homeostasis