ABCG4 antibody (Middle Region)

Catalog No. ABIN3030064

Product Details anti-ABCG4 Antibody

Target: ABCG4 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCG4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the middle region of human ABCG4 (AVQNGLCAMAEKKSS) was used as the immunogen for this ABCG4 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the ABCG4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the ABCG4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for ABCG4

Target: ABCG4 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4))

Alternative Name: ABCG4 (ABCG4 Products)

Synonyms: WHITE2 antibody, 6430517O04Rik antibody, zgc:171697 antibody, ATP binding cassette subfamily G member 4 antibody, ATP-binding cassette sub-family G member 4 antibody, ATP-binding cassette, sub-family G (WHITE), member 4a antibody, ATP-binding cassette, sub-family G (WHITE), member 4b antibody, ABCG4 antibody, CpipJ_CPIJ007191 antibody, CpipJ_CPIJ012365 antibody, CpipJ_CPIJ012372 antibody, CpipJ_CPIJ014443 antibody, CpipJ_CPIJ019125 antibody, CpipJ_CPIJ020198 antibody, PAAG_06842 antibody, Abcg4 antibody, LOC550918 antibody, abcg4a antibody, abcg4b antibody

Background: ATP-Binding Cassette, Subfamily G, Member 4 is a protein that in humans is encoded by the ABCG4 gene. The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. This protein is a member of the White subfamily and is expressed predominantly in liver tissue. By genomic sequence analysis, Engel et al.(2001) mapped the gene to chromosome 11q23.3. Engel et al.(2001) demonstrated 5-fold induction of ABCG4 following treatment of normal monocyte-derived macrophages with the LXR and RXR agonists 9-cis retinoic acid and 22R hydroxycholesterol. Removal of cholesterol from macrophages by cyclodextrin decreased ABCG4 message levels.

UniProt: Q9H172