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BAG3 antibody (C-Term)

BAG3 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030138
  • Target See all BAG3 Antibodies
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Binding Specificity
    • 15
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 58
    • 23
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 59
    • 3
    • 1
    Rabbit
    Clonality
    • 51
    • 12
    Polyclonal
    Conjugate
    • 28
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    This BAG3 antibody is un-conjugated
    Application
    • 39
    • 22
    • 13
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    An amino acid sequence from the C-terminus of human BAG family molecular chaperone regulator 3 (LEKLEQKAIDVPGQVQ) was used as the immunogen for this Bag3 antibody (100% homologous in human, mouse and rat).
    Isotype
    IgG
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    Discover our top product BAG3 Primary Antibody
  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the BAG3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the BAG3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    BAG3 (BCL2-Associated Athanogene 3 (BAG3))
    Alternative Name
    BAG3 (BAG3 Products)
    Synonyms
    bag3-A antibody, MGC53113 antibody, zgc:100859 antibody, BAG3 antibody, ATBAG3 antibody, BCL-2-associated athanogene 3 antibody, T28J14.160 antibody, T28J14_160 antibody, BAG-3 antibody, BIS antibody, CAIR-1 antibody, MFM6 antibody, AA407278 antibody, Bis antibody, mg638 antibody, BCL2 associated athanogene 3 L homeolog antibody, BCL2-associated athanogene 3 antibody, BCL2 associated athanogene 3 antibody, BCL-2-associated athanogene 3 antibody, Bcl2-associated athanogene 3 antibody, bag3.L antibody, bag3 antibody, BAG3 antibody, Bag3 antibody
    Background
    BAG family molecular chaperone regulator 3 is a member of a conserved family of cyto-protective proteins that bind to and regulate Hsp70 family molecular chaperones. BAG3 mutations are responsible for familial dilated cardiomyopathy. Polymorphisms are also associated with sporadic forms of the disease together with HSPB7 locus. In muscle cells, BAG3 cooperates with the molecular chaperones Hsc70 and HspB8 to induce the degradation of mechanically damaged cytoskeleton components in lysosomes. This process is called chaperone-assisted selective autophagy (CASA) and is essential for maintaining muscle activity in flies, mice and men.
    UniProt
    O95817
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