CCR1 antibody (Chemokine (C-C Motif) Receptor 1) (AA 1-30)

Details for Product anti-CCR1 Antibody No. ABIN3030216
Antigen
Epitope
AA 1-30
19
8
8
7
7
4
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
108
29
3
3
Host
Rabbit
94
13
8
6
1
Clonality
Polyclonal
Conjugate
This CCR1 antibody is un-conjugated
9
8
7
6
3
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
73
49
43
35
28
6
6
4
3
2
2
2
Options
Immunogen A portion of amino acids 1-30 from the human protein was used as the immunogen for this CCR1 antibody.
Isotype Ig Fraction
Purification Antigen affinity purified
Antigen
Alternative Name CCR1 (CCR1 Antibody Abstract)
Background CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
UniProt P32246
Application Notes Titration of the CCR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
Restrictions For Research Use only
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the CCR1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Supplier Images
Image no. 1 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-30) antibody (ABIN3030216) CCR1 antibody flow cytometric analysis of 293 cells (right histogram) compared to a n...
Image no. 2 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-30) antibody (ABIN3030216) CCR1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded h...
Image no. 3 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-30) antibody (ABIN3030216) Western blot analysis of CCR1 antibody and 293 lysate. Predicted size 40-45 kDa
Image no. 4 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-30) antibody (ABIN3030216) CCR1 antibody flow cytometric analysis of 293 cells (right histogram) compared to a n...
Image no. 5 for anti-Chemokine (C-C Motif) Receptor 1 (CCR1) (AA 1-30) antibody (ABIN3030216) Western blot analysis of CCR1 antibody and 293 lysate. Predicted size 40-45 kDa