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N-Cadherin antibody (AA 701-714)

CDH2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030245
  • Target See all N-Cadherin (CDH2) Antibodies
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    Binding Specificity
    • 22
    • 15
    • 14
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 701-714
    Reactivity
    • 133
    • 95
    • 67
    • 21
    • 16
    • 14
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 87
    • 55
    • 4
    • 4
    • 3
    Rabbit
    Clonality
    • 80
    • 73
    Polyclonal
    Conjugate
    • 87
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This N-Cadherin antibody is un-conjugated
    Application
    • 119
    • 58
    • 42
    • 40
    • 31
    • 23
    • 17
    • 15
    • 14
    • 13
    • 12
    • 8
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Antigen affinity
    Immunogen
    Amino acids 701-714 (CQCDSNGDCTDVDR) were used as the immunogen for this N-Cadherin antibody (100% homologous human, mouse and rat).
    Isotype
    IgG
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  • Application Notes
    The stated application concentrations are suggested starting points. Titration of the N-Cadherin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the N-Cadherin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    Alternative Name
    N-Cadherin (CDH2 Products)
    Synonyms
    CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody
    Background
    NCAD is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). Human and mouse nucleotide sequences are 96 % identical. The mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. The human Ncad gene contains 16 exons and its sequence is highly similar to both the mouse gene (including the large first and second introns) and other cadherin genes. Cadherins regulates dendritic spine morphogenesis.
    UniProt
    P19022
    Pathways
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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