FANCF antibody (Fanconi Anemia, Complementation Group F)

Details for Product anti-FANCF Antibody No. ABIN303039, Supplier: Log in to see
Antigen
  • FAF
  • A730016A17
  • RGD1561456
  • Fanconi anemia complementation group F L homeolog
  • Fanconi anemia, complementation group F
  • Fanconi anemia complementation group F
  • fancf.L
  • fancf
  • FANCF
  • Fancf
Reactivity
Human, Monkey
56
5
5
2
2
1
Host
Rabbit
31
20
5
Clonality
Polyclonal
Conjugate
This FANCF antibody is un-conjugated
3
3
3
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
50
44
10
7
4
3
1
Options
Supplier
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Immunogen Synthetic peptide
Specificity This antibody reacts to an internal amino acid sequence of FANCF.
Purification Immunoaffinity Chromatography
Plasmids, Primers & others Plasmids, Primers & others FANCF products on genomics-online (e.g. as negative or positive controls)
Alternative Name FANCF (FANCF Antibody Abstract)
Background FANCF (also called Protein FACF or Fanconi Anemia Group F protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCF has also been implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. FANCF belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients. FANCF is found within the nucleus. Defects in FANCF are a cause of Fanconi anemia (FA). FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopaenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level, it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.Synonyms: FACF, Fanconi anemia group F protein
Gene ID 2188
NCBI Accession NP_073562
UniProt Q9NPI8
Application Notes Immunofluorescence. Immunohistochemistry on paraffin secton: 2,5 μg/mL. Western Blot. ELISA: 1: 15000 - 1: 60000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
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