CD82 antibody (AA 98-267)

Catalog No. ABIN3030428

Product Details anti-CD82 Antibody

Target: CD82

Binding Specificity: AA 98-267

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD82 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Humanpartial recombinant protein (AA 98-267) was used as the immunogen for this CD82 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the CD82 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CD82 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for CD82

Target: CD82

Alternative Name: CD82 (CD82 Products)

Synonyms: AA682076 antibody, AL023070 antibody, C33 antibody, IA4 antibody, Kai1 antibody, Tspan27 antibody, 4F9 antibody, GR15 antibody, KAI1 antibody, R2 antibody, SAR2 antibody, ST6 antibody, TSPAN27 antibody, CD82 antigen antibody, CD82 molecule antibody, Cd82 molecule antibody, Cd82 antibody, CD82 antibody

Background: Cluster of Differentiation 82, also called KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression has been shown to be downregulated in tumor progression of human cancers and can be activated by < a href=../search_result.php?search_txt=p53>p53 through a consensus binding sequence in the promoter. The expression of CD82 appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And overexpression can suppress tumor invasiveness and metastatic potential by inducing < a href=../search_result.php?search_txt=mmp9>MMP9 inactivation via upregulation of < a href=../search_result.php?search_txt=timp1>TIMP1.

Gene ID: 3732

Pathways: p53 Signaling