beta Defensin 1 antibody (C-Term)

Catalog No. ABIN3030708

Product Details anti-beta Defensin 1 Antibody

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta Defensin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human beta Defensin 1 (FTKIQGTCYRGKAKCCK) was used as the immunogen for this beta Defensin 1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the beta Defensin 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the beta Defensin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for beta Defensin 1

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Alternative Name: beta Defensin 1 (DEFB1 Products)

Synonyms: BD1 antibody, DEFB-1 antibody, DEFB101 antibody, HBD1 antibody, AW260221 antibody, BD-1 antibody, DEFB1-like antibody, RHBD-1 antibody, CBD1 antibody, PBD-1 antibody, DEFB1 antibody, BNBD-1 antibody, defensin beta 1 antibody, avian beta-defensin 1 antibody, defensin, beta 1 antibody, beta-defensin 1-like antibody, beta-defensin 1 antibody, DEFB1 antibody, Defb1 antibody, AvBD1 antibody, LOC100861170 antibody

Background: Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1 gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1 may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

UniProt: P60022