Dystrophin antibody (AA 3076-3404)

Catalog No. ABIN3030782

Product Details anti-Dystrophin Antibody

Target: Dystrophin (DMD)

Binding Specificity: AA 3076-3404

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystrophin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 3076-3404) was used as the immunogen for this Dystrophin antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the Dystrophin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the Dystrophin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Dystrophin

Target: Dystrophin (DMD)

Alternative Name: Dystrophin (DMD Products)

Synonyms: DMD antibody, Dmd antibody, MGC83347 antibody, DKFZp459C1629 antibody, dmd antibody, MGC79631 antibody, DKFZp468A1620 antibody, Dp71 antibody, cb664 antibody, zfDYS antibody, im:6911785 antibody, zgc:110165 antibody, BMD antibody, CMD3B antibody, DXS142 antibody, DXS164 antibody, DXS206 antibody, DXS230 antibody, DXS239 antibody, DXS268 antibody, DXS269 antibody, DXS270 antibody, DXS272 antibody, DXSmh7 antibody, DXSmh9 antibody, Dp427 antibody, dys antibody, mdx antibody, pke antibody, DNADMD1 antibody, RATDMD antibody, CG17750 antibody, CG31175 antibody, CG34157 antibody, CG7240 antibody, CG7243 antibody, CG7344 antibody, DLP antibody, DLP1 antibody, DLP186 antibody, DLP2 antibody, DLP3 antibody, DmDLP antibody, DmDYS antibody, Dmel\\CG34157 antibody, Dp117 antibody, Dp186 antibody, Dp205 antibody, GI3046716 antibody, IDLP antibody, det antibody, dmDLP antibody, dmDp186 antibody, dmDys antibody, dystrophin antibody, dystrophin, gene 1 L homeolog antibody, dystrophin, gene 1 antibody, dystrophin, muscular dystrophy antibody, Dystrophin antibody, DMD antibody, LOC708073 antibody, dmd.1.L antibody, LOC465557 antibody, dmd.1 antibody, dmd antibody, Dmd antibody, Dys antibody

Background: Dystrophin, also known as DMD, is a rod-shaped cytoplasmic protein, and a vital part of a protein complex that connects the cytoskeleton of a muscle fiber to the surrounding extracellular matrix through the cell membrane. It is mapped to Xp21.2-p21.1. This complex is variously known as the costamere or thedystrophin-associated protein complex. Many muscle proteins, such as alpha-dystrobrevin, syncoilin, synemin, sarcoglycan, dystroglycan, and sarcospan, colocalize with Dystrophin at the costamere. Dystrophin is a protein located between the sarcolemma and the outermost layer of myofilaments in the muscle fiber (myofiber). It is a cohesive protein, linking actin filaments to another support protein that resides on the inside surface of each muscle fiber's plasma membrane (sarcolemma).

Gene ID: 1756

Pathways: Skeletal Muscle Fiber Development