FOSB antibody (N-Term)

Catalog No. ABIN3030918

Product Details anti-FOSB Antibody

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of human FosB (MFQAFPGDYDSGSRC) was used as the immunogen for this FosB antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FosB antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FosB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: FosB (FOSB Products)

Synonyms: FOSB antibody, zgc:92354 antibody, AP-1 antibody, G0S3 antibody, GOS3 antibody, GOSB antibody, fra-2 antibody, FBJ murine osteosarcoma viral oncogene homolog B antibody, FosB proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene B antibody, FOSB antibody, fosb antibody, Fosb antibody

Background: FBJ murine osteosarcoma viral oncogene homolog B is a protein that in humans is encoded by the FOSB gene. It is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Delta FOSB is a truncated splice variant of FOSB. It has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. It also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

UniProt: P53539