FCAR antibody (Middle Region)

Catalog No. ABIN3030919

Product Details anti-FCAR Antibody

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCAR antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the middle of human CD89 (EFVIDHMDANKAGRYQCQ) was used as the immunogen for this CD89 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the CD89 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the CD89 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FCAR

Target: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Alternative Name: CD89 (FCAR Products)

Synonyms: CD89 antibody, Fc fragment of IgA receptor antibody, Fc fragment of IgA, receptor for antibody, FCAR antibody

Background: FCAR, Receptor for Fc fragment of IGA, is also known as CD89. It is a glycoprotein of 50-100 kD present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. CD89 interacts with aggregated IgAs (but not IgGs), such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators.

UniProt: P24071