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FCER2 antibody (AA 50-331)

FCER2 Reactivity: Human, Mouse, Rat WB, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3030920
  • Target See all FCER2 Antibodies
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Binding Specificity
    • 17
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-331
    Reactivity
    Human, Mouse, Rat
    Host
    • 57
    • 47
    • 16
    Rabbit
    Clonality
    • 76
    • 42
    • 2
    Polyclonal
    Conjugate
    • 57
    • 16
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCER2 antibody is un-conjugated
    Application
    • 72
    • 52
    • 33
    • 20
    • 13
    • 10
    • 10
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Antigen affinity
    Immunogen
    Mouse partial recombinant protein (AA 50-331) was used as the immunogen for this CD23 antibody.
    Isotype
    IgG
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  • Application Notes
    The stated application concentrations are suggested starting amounts. Titration of the CD23 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL
    Restrictions
    For Research Use only
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Storage
    -20 °C
    Storage Comment
    After reconstitution, the CD23 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Alternative Name
    CD23 (FCER2 Products)
    Synonyms
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    Background
    CD23, also known as Fc epsilon RII, or Fc< font face=symbol>eRII, is the low-affinity receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages. As part of a mapping of multiple probes to specific bands on chromosome 19 by fluorescence in situ hybridization, the FCE2 gene was assigned to 19p13.3. CD23 is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.
    Gene ID
    14128
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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