Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Connexin 43/GJA1 antibody (Gap Junction Protein, alpha 1, 43kDa) (AA 107-138) Primary Antibody

GJA1 Reactivity: Human, Mouse, Rat IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031020
$521.13
Plus shipping costs $45.00
0.4 mL ABIN3031020
0.4 mL ABIN3031020
local_shipping Shipping to: United States
Delivery in 2 to 3 Business Days
  • Target
    Connexin 43/GJA1 (GJA1)
    Binding Specificity
    • 22
    • 16
    • 14
    • 12
    • 8
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-138
    Reactivity
    • 140
    • 96
    • 91
    • 35
    • 13
    • 12
    • 10
    • 10
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 134
    • 10
    • 10
    Rabbit
    Clonality
    • 142
    • 11
    Polyclonal
    Conjugate
    • 88
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Connexin 43/GJA1 antibody is un-conjugated
    Application
    • 105
    • 57
    • 52
    • 29
    • 20
    • 18
    • 13
    • 13
    • 10
    • 10
    • 9
    • 6
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Bovine, Xenopus
    Purification
    Purified
    Immunogen
    A portion of amino acids 107-138 from the human protein was used as the immunogen for this Connexin 43 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the Connexin 43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the Connexin 43 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Connexin 43/GJA1 (GJA1)
    Alternative Name
    Connexin 43 (GJA1 Antibody Abstract)
    Synonyms
    AVSD3, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD, Cx43, AU042049, AW546267, Cnx43, Cx43alpha1, Gja-1, Npm1, connexin43, cx43a1, gja1, zfCx43.3, connexin 43, gja1-A, cx43, gjal, oddd, dfnb38, gap junction protein alpha 1, gap junction protein, alpha 1, connexin 43, gap junction protein alpha 1 L homeolog, CONNEXIN 43 protein, GJA1, Gja1, cx43, gja1.L, gja1, CONNEXIN 43
    Background
    Gap junction protein, alpha 1 is a member of the connexin gene family and a component of gap junctions. Gap junctions are composed of arrays of intercellular channels and provide a route for the diffusion of materials of low molecular weight from cell to cell. Connexin 43 is the major protein of gap junctions in the heart, and gap junctions are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. Connexin 43 is targeted by several protein kinases that regulate myocardial cell-cell coupling. A related intron-less connexin 43 pseudogene, GJA1P, has been mapped to chromosome 5.
    UniProt
    P17302
    Pathways
    MAPK Signaling, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
You are here:
help Support