Glutamate Receptor 1 antibody (AA 19-360)

Catalog No. ABIN3031064

Product Details anti-Glutamate Receptor 1 Antibody

Target: Glutamate Receptor 1 (GLUR1)

Binding Specificity: AA 19-360

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 19-360) was used as the immunogen for this GLUR1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the GLUR1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the GLUR1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: GLUR1 (GLUR1 Products)

Synonyms: GLUH1 antibody, GLUR1 antibody, GLURA antibody, GluA1 antibody, HBGR1 antibody, gluR-A antibody, 2900051M01Rik antibody, Glr-1 antibody, Glr1 antibody, GluR-A antibody, GluRA antibody, Glur-1 antibody, Glur1 antibody, HIPA1 antibody, gluR-K1 antibody, GRIA1 antibody, glur1 antibody, Gria1 antibody, glur1b antibody, gria1.2 antibody, sb:eu293 antibody, ZfGluR1a antibody, glur1a antibody, gria1.1 antibody, zfGRIA1[a] antibody, glutamate ionotropic receptor AMPA type subunit 1 antibody, glutamate receptor, ionotropic, AMPA1 (alpha 1) antibody, glutamate receptor, ionotropic, AMPA 1 antibody, glutamate receptor, ionotropic, AMPA 1 L homeolog antibody, GluR1 protein antibody, Glutamate receptor 1 antibody, glutamate receptor, ionotropic, AMPA 1b antibody, glutamate receptor, ionotropic, AMPA 1a antibody, GRIA1 antibody, Gria1 antibody, gria1 antibody, gria1.L antibody, glur1 antibody, glr-1 antibody, gria1b antibody, gria1a antibody

Background: Glutamate receptor 1 is a protein that in humans is encoded by the GLUR1 gene. mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. GLUR1/GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GLUR1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties.

Gene ID: 2890

Pathways: PI3K-Akt Signaling