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IL1R1 antibody (Interleukin 1 Receptor, Type I) (AA 474-503) Primary Antibody

IL1R1 Reactivity: Human IHC, ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3031431
$507.38
Plus shipping costs $45.00
0.4 mL ABIN3031431
0.4 mL ABIN3031431
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  • Target
    IL1R1
    Binding Specificity
    • 21
    • 19
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 474-503
    Reactivity
    • 107
    • 54
    • 36
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 107
    • 19
    • 10
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 106
    • 37
    Polyclonal
    Conjugate
    • 75
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL1R1 antibody is un-conjugated
    Application
    • 91
    • 81
    • 39
    • 37
    • 16
    • 15
    • 13
    • 13
    • 11
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
    Cross-Reactivity (Details)
    Expected species reactivity: Rat
    Purification
    Antigen affinity purified
    Immunogen
    A portion of amino acids 474-503 from human IL-1 Receptor type 1 was used as the immunogen for this IL1R1 antibody.
    Isotype
    Ig Fraction
  • Application Notes
    Titration of the IL1R1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Aliquot the IL1R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    IL1R1
    Alternative Name
    IL-1 Receptor type 1 (IL1R1 Antibody Abstract)
    Synonyms
    CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80, CD121a, CD121b, IL-iR, Il1r-1, interleukin 1 receptor type 1, interleukin 1 receptor, type I, IL1R1, Il1r1
    Background
    IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
    UniProt
    P14778
    Pathways
    NF-kappaB Signaling, Carbohydrate Homeostasis, Cancer Immune Checkpoints
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