KLK11
Reactivity: Human
IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
The stated application concentrations are suggested starting amounts. Titration of the Kallikrein-11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the Kallikrein-11 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Kallikrein-11, also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. It is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The gene contains 6 exons, the first of which is noncoding. KLK11 shares 48 % amino acid sequence identity with mouse neuropsin, 43 % identity with both human trypsin-1 and human kallikrein, and 38 % identity with the mouse nerve growth factor gamma subunit. Alternate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Western blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.